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South San Francisco
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South San Francisco · development

Development activity

Active development applications and projects in South San Francisco, ranked by community impact.

18 applications4 types
PendingConditional Use

Handicraft/Custom Manufacturing Use, 180 S Spruce Avenue, Suite C

180 S Spruce Avenue, Suite C, South San Francisco, CA

1 hearing0 commentsLast discussed Nov 3, 2026
ApprovedOther

Master Sign Program — 1400 Huntington Avenue (formerly 410 Noor Avenue)

1400 Huntington Avenue, South San Francisco, CA

1 hearing0 commentsLast discussed Oct 15, 2026
ApprovedOther

Master Sign Program Amendment — Genesis Campus, 1-3 Tower Place

1-3 Tower Place, South San Francisco, CA

1 hearing0 commentsLast discussed Oct 15, 2026
ApprovedOther

Rotary Gardens Affordable Senior Housing

Rotary Plaza, Inc. / Rotary Gardens, L.P.

500 Linden Avenue

1 hearing0 commentsLast discussed Sep 30, 2026
ApprovedOther

Fire Station 63 — Westborough Boulevard Acceptance

Westborough Boulevard near Camaritas Avenue

1 hearing0 commentsLast discussed Sep 30, 2026
ApprovedConditional Use

Genentech Research and Early Development Center (gRED Center)

Genentech, Inc.

Genentech Campus, Oyster Point, South San Francisco, CA

2 hearings0 commentsLast discussed Sep 3, 2026
ApprovedSite Plan

Fire Station 63 (Project P25-0116)

City of South San Francisco

71 Camaritas Avenue, South San Francisco, CA

2 hearings0 commentsLast discussed Jul 8, 2026
ApprovedOther

Alexandria Center for Advanced Technologies Campus Master Sign Program

Alexandria

249-281 E. Grand Avenue, South San Francisco, CA

1 hearing0 commentsLast discussed Jun 18, 2026
ApprovedOther

Summary vacation of public utility easements — Cypress and Miller Avenues

405 Cypress Avenue; 204, 208, 214, 216 Miller Avenue

1 hearing0 commentsLast discussed May 13, 2026
ApprovedOther

First Major Amendment to Development Agreement — 1051 Mission Road (PUC Site)

1051 Mission Road

2 hearings0 commentsLast discussed May 13, 2026
ApprovedOther

1051 Mission Road (PUC Site)

SSF PUC Housing Partners, LLC (L37 and CASA); BRIDGE Housing (outgoing)

1051 Mission Road, South San Francisco, CA

2 hearings0 commentsLast discussed Apr 22, 2026
ApprovedSubdivision

616 Maple Avenue Tentative Subdivision Map (SA26-0001)

616 Maple Avenue, South San Francisco, CA

1 hearing0 commentsLast discussed Apr 16, 2026
ApprovedConditional Use

Hookah Lounge and Private Events Permit, 1429 San Mateo Avenue

Nizarine Carmi (applicant representative)

1429 San Mateo Avenue, South San Francisco, CA

1 hearing1 commentLast discussed Mar 19, 2026
ApprovedConditional Use

Hookah Lounge and Private/Special Event Use, 1429-1431 San Mateo Avenue

Nizrine Carmi

1429-1431 San Mateo Avenue, South San Francisco, CA

1 hearing2 commentsLast discussed Mar 19, 2026
Under-reviewSite Plan

Four-unit apartment building at 227 Armour Avenue

227 Armour Avenue, South San Francisco, CA

1 hearing0 commentsLast discussed Mar 18, 2026
ApprovedOther

Summary vacation of Public Utility Easements — 972 and 932 El Camino Real

972 and 932 El Camino Real, South San Francisco, CA

1 hearing0 commentsLast discussed Feb 25, 2026
ApprovedSite Plan

Westborough Preschool Expansion Project

City of South San Francisco

2360 Galway Drive, South San Francisco, CA

1 hearing0 commentsLast discussed Feb 19, 2026
ApprovedOther

Rotary Gardens Phase 1 (500 Linden Avenue)

Rotary Club of South San Francisco / Beacon Development Group

500 Linden Avenue, South San Francisco, CA

2 hearings0 commentsLast discussed Jan 14, 2026